Table 2.

Association between polygenic risk scores (PRS) and ovarian cancer in different age groups

Age group	Overall		Serous
	OR (95% CI)	P values	OR (95% CI)	P values
All ages	1.32 (1.21 to 1.45)	5.38×10–10	1.43 (1.29 to 1.58)	1.28×10–11
<60	1.29 (0.91 to 1.86)	0.16	1.46 (1.01 to 2.17)	0.05
60–69	1.28 (1.11 to 1.49)	8.99×10–4	1.34 (1.14 to 1.59)	4.51×10–4
≥70	1.36 (1.20 to 1.55)	3.02×10–6	1.47 (1.26 to 1.72)	7.10×10–7
Interaction	1.00 (0.99 to 1.02)	0.88	1.00 (0.98 to 1.02)	0.95

In the overall PRS analysis, we used cases of any type of ovarian cancers and in the serous PRS analysis we used cases of serous ovarian cancer.