Table 1.
List of important DAMPs members and their receptors.
| Sr. # | DAMPs | Receptors |
|---|---|---|
| 1. | HMGB1 | TLR-2, TLR-4, TLR-9, RAGE |
| 2. | IL-1α | IL-1R |
| 3. | IL-33 | ST2 (IL-1RL1) |
| 4. | Heme, Hemin, Oxyhemoglobin, methemoglobin | TLR-4 |
| 5. | mtDNA | TLR-9, NLRP3, NLRC4, AIM-2, cGAS-STING |
| 6. | TFAM | RAGE, TLR-9 |
| 7. | N-formyl peptides | FPR1, FPRL1 |
| 8. | S-100 proteins | TLR-4, RAGE |
| 9. | Fibrinogen | TLR-4 |
| 10. | Fibronectin | TLR-2, TLR-4 |
| 11. | Hyaluronan | TLR-2, TLR-4 |
| 12. | Biglycan | TLR-2, TLR-4, P2X4, P2X7, NLRP3 |
| 13. | Versican | TLR-2, TLR-6, CD14 |
| 14. | Heparan sulfate | TLR-4 |
| 15. | Tenascin C | TLR-4 |
| 16. | Galectin-3 | TLR-2, TLR-4 |