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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Shock. 2018 Jul;50(1):53–59. doi: 10.1097/SHK.0000000000001029

Table 5.

Population-specific Paraclique: White Patients Diagnosed with Community-acquired pneumonia

GENE FUNCTION
CCRN4L; carbon catabolite repression 4-like Component of the circadian clock
CRISP3; cysteine-rich secretory protein 3 CRISP-3 in peroxidase-negative granules of neutrophils, in granules of eosinophils, and in exocrine secretions
FUT4; fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens
IGFBP2; insulin-like growth factor binding protein 2 Inhibits IGF-mediated growth and developmental rates
KIAA1024
KLHDC7B; kelch domain containing 7B
PRG2; proteoglycan 2 Induces non-cytolytic histamine release from human basophils. Antiparasitic defense and immune hypersensitivity reactions
PRSS21; protease, serine, 21 May regulate proteolytic events associated with testicular germ cell maturation
PTP4A3; protein tyrosine phosphatase type IVA, member 3 Stimulates progression from G1 into S phase. Enhances cell proliferation, cell motility and invasion activity M
STOX2; storkhead box 2
PRSSL1/KLK10; kallikrein-related peptidase 10 Has a tumor-suppressor role for NES1 in breast and prostate cancer
CEACAM8 aka CD67; carcinoembryonic antigen-related cell adhesion molecule 8n Expressed on granuolocytes and leukemic cells
LPAR4; lysophosphatidic acid receptor 4 Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity
ITPKA; inositol-trisphosphate 3-kinase A Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4.