Skip to main content
. Author manuscript; available in PMC: 2018 Aug 3.
Published in final edited form as: JACC Clin Electrophysiol. 2018 Feb 2;4(4):504–514. doi: 10.1016/j.jacep.2017.12.003

FIGURE 5. Immunohistochemistry of Left Ventricular Myocardial Tissue.

FIGURE 5

Immunostaining of the explanted heart of patient DNFDC057-II:2 carrying the G1891Vfs61X FLNC truncation. (A) Immunoreactive signals for plakoglobin and connexin 43 (Cx43) at intercalated discs are normal compared with control samples, whereas junctional signal for desmoplakin is reduced. N-cadherin is used as a tissue quality control and is normal in all samples. (B) SAP97 signal is depressed compared with control samples. GSK3β maintained its normal cytoplasmic distribution.