Table 2.

Primary maternal-fetal outcomes in patients with r-AKI vs no AKI.

Outcome	r-AKI (N=246)			No AKI N=14,240	Unadjusted Odds	Adjusted Odds
Outcome	Stage 1 N=98	Stage 2 N=99	Stage 3 N=49	No AKI N=14,240	Unadjusted Odds	Adjusted Odds
Maternal Outcomes
Cesarean section	38% (94)			31% (4,430)	1.4 [1.1-1.8]	1·3 [0.9-1.9]	p=0.190
Cesarean section	36% (35)	40% (40)	39% (19)	31% (4,430)	1.4 [1.1-1.8]	1·3 [0.9-1.9]	p=0.190
Preeclampsia	22% (55)			9% (1,274)	3.0 [2.2-4.0]	2·9 [1.9-4.4]	p<0.001
Preeclampsia	12% (12)	23% (23)	40% (20)	9% (1,274)	3.0 [2.2-4.0]	2·9 [1.9-4.4]	p<0.001
Preterm Preeclampsia (<37 weeks)	9% (22)			2% (330)	4.1 [2.6-6.5]	3·6 [1.8-7.1]	p<0.001
Preterm Preeclampsia (<37 weeks)	4% (4)	9% (9)	18% (20)	2% (330)	4.1 [2.6-6.5]	3·6 [1.8-7.1]	p<0.001
Early Preterm Preeclampsia (<34 weeks)	4% (9)			1% (95)	5.7 [2.8-11.3]	1·2 [0.2-8.7]	p=0.878
Early Preterm Preeclampsia (<34 weeks)	1% (1)	4% (4)	8% (4)	1% (95)	5.7 [2.8-11.3]	1·2 [0.2-8.7]	p=0.878
Gestational Hypertension	22% (51)			12% (1,621)	2.0 [1.5-2.7]	2.3 [1.7-3.3]	p<0.001
Gestational Hypertension	12% (12)	25% (24)	33% (15)	12% (1,621)	2.0 [1.5-2.7]	2.3 [1.7-3.3]	p<0.001
Fetal Outcomes
Gestation age at delivery – weeks	38.2±3.0			39.0±22	n/a	n/a	p<0.001
Gestation age at delivery – weeks	38.7±2.4	38.1±3.3	37.1±3.5	39.0±22	n/a	n/a	p<0.001
Baby weight – grams	3,010±690			3,350±620	n/a	n/a	p<0.001
Baby weight – grams	3,240±600	3,040±730	2,940±730	3,350±620	n/a	n/a	p<0.001
Birth weight <10^th percentile	20% (50)			9% (1,299)	2.5 [1.8-3.5]	2.7 [1.7-4.3]	p<0.001
Birth weight <10^th percentile	16% (16)	24% (24)	20% (10)	9% (1,299)	2.5 [1.8-3.5]	2.7 [1.7-4.3]	p<0.001
Birth weight <5^h percentile	9% (23)			5% (718)	1.5 [0.9-2.4]	2.2 [1.4-3.4]	p=0.001
Birth weight <5^h percentile	7% (7)	10% (10)	12% (6)	5% (718)	1.5 [0.9-2.4]	2.2 [1.4-3.4]	p=0.001
Birth weight <3^rd percentile	3% (8)			3% (397)	1.2 [0.6-2.4]	1.3 [0.6-2.6]	p=0.495
Birth weight <3^rd percentile	***	***	***	3% (397)	1.2 [0.6-2.4]	1.3 [0.6-2.6]	p=0.495
Perinatal Death	****			1% (108)	2.2 [0.8-5.9]	1.9 [0.7-5.5]	p=0.209
Neonatal ICU Admission	19% (46)			10% (1,364)	2.2 [1.6-3.0]	2.0 [1.4-2.8]	p<0.001
Neonatal ICU Admission	13% (13)	19% (19)	30% (14)	10% (1,364)	2.2 [1.6-3.0]	2.0 [1.4-2.8]	p<0.001
Composite Fetal Outcome	39% (96)			18% (2,621)	2.3 [1.8-3.1]	1.9 [1.4-2.6]	p<0.001
Composite Fetal Outcome	25% (25)	32% (32)	39% (19)	18% (2,621)	2.3 [1.8-3.1]	1.9 [1.4-2.6]	p<0.001

Data are presented as % (n), the mean ± SD and OR (95% CI). Gestational hypertension outcome included only for women without pre-existing hypertension. Outcomes are adjusted for age, race, BMI, diastolic blood pressure at first prenatal visit, history of diabetes and parity. P-values reflect the adjusted analysis for dichotomous outcome variables and t-tests between for continuous outcome variables entire r-AKI cohort and no AKI cohort. Numbers of perinatal deaths and birthweight < 3^rd percentile in r-AKI group suppressed to preserve confidentiality due to low numbers.