Table 1.

Prevalence of major congenital anomalies in 45 682 children.

	Male	Female	Total	Prevalence per 10 000
Down syndrome	14	16	30	6.6
Congenital deafness	11	11	22	4.8
Congenital blindness	5	1	6	1.3
Cleft lip/palate	4	0	4	0.9
Achondroplasia	2	1	3	0.7
Multiple congenital anomalies	3	0	3	0.7
Dandy-Walker syndrome	2	0	2	0.4
Crouzon syndromea	1	0	1	0.2
Treacher-Collins syndrome	1	0	1	0.2
Angelman syndromeb	1	0	1	0.2
Turner syndrome	0	1	1	0.2
Absent uvula	1	0	1	0.2
Congenital diaphragmatic hernia	1	0	1	0.2
Imperforated anus	1	0	1	0.2

^aCrouzon syndrome; AD, branchial arch syndrome.

^bAngelman syndrome; neurogenetic disorder characterized by severe intellectual and developmental delay.