Table 2.
Prevalence of inherited and acquired thrombophilia in normal pregnancy and women with preeclampsia and eclampsia.
| Thrombophilia | Preeclampsia and eclampsia (n=100) | Normal Pregnancy (n=100) | Odds ratio (95%CI) | P |
|---|---|---|---|---|
| Factor V Leiden mutation (heterozygous) | 6 | 4 | 1.5 (0.4–5.1) | 0.748 |
| Prothrombin mutation (heterozygous) | 4 | 1 | 4.0 (0.4–35.1) | 0.369 |
| Prothrombin mutation (homozygous) | 0 | 1 | 1.0 (0.9–1.0) | 1.0 |
| MTHFR (homozygous) | 16 | 12 | 1.3 (0.6–2.6) | 0.271 |
| All genetic mutations | 26 | 16 | 1.6 (0.9–2.8) | 0.118 |
| Protein S | 14 | 12 | 1.1(0.5–2.3) | 0.834 |
| Protein C | 1 | 0 | 1.0 (0.9–1.0) | 1.0 |
| Antithrombin III | 1 | 0 | 1.0 (0.9–1.0) | 1.0 |
| All thrombophilia | 42 | 28 | 1.5(1.0–2.2) | 0.27 |