Table 4.
Multinomial logistic regression analysis of factors associated with different types of nephropathy.
| Risk factors | Microalbuminuria | Macroalbuminuria | ESRD | |||
|---|---|---|---|---|---|---|
| Odds Ratio | P value | Odds Ratio | P value | Odds Ratio | P value | |
|
| ||||||
| Uric acid for males >6.8 mg/dL | 6.30 (2.25–17.54) | <.001 | 3.97 (1.58–9.99) | <.001 | 13.42 (5.04–35.70) | <.001 |
| Uric acid for females >6.0 mg/ dL | 4.70 (2.04–10.83) | <.001 | 1.67 (0.82–3.41) | .161 | 11.30 (4.90–26.09) | <.001 |
| LDH >190 U/L | 2.33 (1.23–4.39) | .009 | 1.37 (0.81–2.32) | .246 | 7.34 (4.19–12.85) | <.001 |
| HOMA-IR ≥4.32 | 1.85 (0.86–3.96) | .116 | 2.11 (1.23–3.62) | .007 | 2.57 (1.34–4.90) | .004 |
| WBCs count >11 109/L | 1.82 (0.57–5.86) | .313 | 1.41 (0.52–3.78) | .499 | 1.10 (0.32–3.75) | .877 |
| RBCs count <4.7 1012/L | 1.190 (0.72–1.99) | .496 | 2.40 (1.20–4.78) | .013 | 13.26 (5.83–30.15) | <.001 |
| Hemoglobin for females <12% | 1.14 (0.56–2.32) | .718 | 2.82 (1.07–7.38) | .035 | 7.77 (3.33–18.12) | <.001 |
| RDW ≥14.5% | 0.72 (0.38–1.38) | .329 | 0.87 (0.54–1.39) | .562 | 2.84 (1.70–4.74) | <.001 |
| Hemoglobin for males <13% | 0.71 (0.26–1.96) | .508 | 3.62 (1.20–4.78) | .019 | 19.66 (5.89–65.60) | <.001 |
| Hct ≥52% | 0.57 (0.11–2.87) | .497 | 1.45 (0.57–3.69) | .437 | 1.01 (0.33–3.15) | .981 |
Hb: hemoglobin; Hct: hematocrit; HOMA B: homeostatic model assessment b-cell function (B); HOMA IR: homeostatic model assessment insulin resistance LDH: lactate dehydrogenase; RBC: red blood cells; RDW: Red blood cell distribution width; WBC: white blood cells.
Adjust for age, diabetes duration, BMI, SBP and DBP.
Model-fitting information: −2 Log Likelihood:Uric Acid for males >6.8 μmol/L: 772.2; Uric Acid for females ≥6.8 μmol/L: 772.2; 1670.0; LDH >190 U/L: 1670.0; HOMA-IR ≥4.32: 1057.5; WBCs count >11×109/L:1635.8; RBCs<4.7 1012 /L: 1622.6; Hemoglobin for females <12%: 857.8; RDW ≥14.5%: 1498.6; Hemoglobin for Male <13%: 758.0; HCT ≥ 53%: 622.2