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. 2017 Sep-Oct;37(5):375–385. doi: 10.5144/0256-4947.2017.375

Table 4.

Strategies used to minimize the impact of drug shortages on patient safety and care by hospital sector.

Strategy Hospital Sector Total (n=120)
MOH hospitals (n=29) MOH-affiliated medical cities (n=38) Non-MOH hospitals (n=53) P value

Substitute (without consultation with the prescriber/the patient) 6 (20.69) 8 (21.05) 8 (15.09) .716 22 (18.33)
Inform prescriber and recommend an alternative drug 17 (58.62) 28 (73.68) 42 (79.25) .132 87 (72.50)
Inform the prescriber of the drug shortage 7 (24.14) 15 (39.47) 28 (52.83) .039 50 (41.67)
Investigate when supply will be restored and plan stock accordingly 6 (20.69) 11 (28.95) 28 (52.83) .006 45 (37.50)
Attempt to source the medicine from an alternative supplier (including another hospital) 5 (17.24) 11 (28.95) 21 (39.62) .105 37 (30.83)
Change the formulary based on the information provided 4 (13.79) 0 (0.00) 3 (5.66) .036 7 (5.83)
Reassign staff work profiles and job descriptions (e.g., devote staff resources more specifically to dealing
with shortages) 12 (41.38) 15 (39.47) 21 (39.62) .984 48 (40.00)
Create new communication systems and tools to alert prescribers and other hospital staff about the presence of shortages and the need to substitute replacement therapies 21 (72.41) 29 (76.32) 41 (77.36) .879 91 (75.83)
Readjust budget plans due to additional expenditure caused by shortages (e.g., needing to use more expensive replacement therapies) 14 (48.28) 13 (34.21) 22 (41.51) .505 49 (40.83)
Cancel practice improvement and development initiatives due to resources having to be reassigned to dealing with the shortages problem 7 (24.14) 4 (10.53) 10 (18.87) .3273 21 (17.50)
No changes required 2 (6.90) 3 (7.89) 2 (3.77) .690 7 (5.83)