Table 3.

First-cousin consanguinity and genetic diseases in children.

Condition	First cousins n=3882 (%)	Nonconsanguineous n=5084 (%)	Odds ratio (95% confidence interval)	P value
Down syndrome	10 (0.026)	9 (0.018)	1.46 (0.55–3.89)	.55
Sickle cell disease	19 (0.049)	24 (0.047)	1.04 (0.54–1.97)	.97
G6PD deficiency	13 (0.033)	21 (0.041)	0.81 (0.38–1.69)	.67
Congenital malformations	49 (1.26)	42 (0.083)	1.53 (0.99–2.37)	.05
Congenital heart disease	34 (0.088)	22 (0.043)	2.03 (1.15–3.60)	.01
Type 1 diabetes mellitus	11 (0.028)	15 (0.029)	0.96 (0.41–2.21)	.92