Table 1.

Four statistical models used to investigate which regional brain volumes are smaller for HIV+ individuals with DNP compared to HIV+ individuals without DNP as well as HIV+ individuals with larger DNP ratings. Models #2 and #4 control for covariates previously associated with changes in total cortical volume [24]—these control covariates are listed in Table 2

	Unadjusted models not controlling for covariates associated with changes in total cortical volume	Adjusted models controlling for covariates associated with changes in total cortical volume
Statistical models investigating regional brain volumes smaller for individuals with DNP vs individuals without DNP	Model #1	Model #2
Statistical models investigating smaller regional brains in HIV+ individuals with larger DNP ratings	Model #3	Model #4