Table 3.
Demographic and clinical characteristics of the participants. Column 5 lists the P values showing if the characteristic proportions or mean values are significantly different for individuals with DNP compared to individuals without DNP
| DNP | All individuals | DNP | No DNP | P values DNP vs no DNP |
|---|---|---|---|---|
| No. of individuals | 233 | 64 | 169 | |
| Neuropathic pain rating, no. (%) | ||||
| No pain | 169 (73) | 0 (0) | 169 (100) | |
| Slight | 18 (8) | 18 (11) | 0 (0) | |
| Mild | 22 (9) | 22 (13) | 0 (0) | |
| Moderate | 9 (4) | 9 (5) | 0 (0) | |
| Severe | 15 (6) | 15 (90) | 0 (0) | |
| Age, mean (SD) | 44 (8) | 46 (8) | 43 (8) | <0.01* |
| Education yrs, mean (SD) | 13 (3) | 13 (2) | 13 (2) | 0.734 |
| Male, no. (%) | 187 (80) | 50 (78) | 137(81) | 0.712 |
| Race/ethnicity, no. (%) | ||||
| Caucasian | 92 (40) | 32 (50) | 60 (36) | 0.211 |
| African American | 110 (47) | 24 (38) | 86 (61) | |
| Hispanic | 26 (11) | 7 (11) | 19 (11) | |
| Other | 5 (2) | 1 (2) | 4 (2) | |
| Hepatitis C Virus seropositive, no. (%) | 64 (28) | 21 (33) | 43 (25) | 0.324 |
| AIDS, no. (%) | 147(63) | 41 (64) | 106(63) | 0.880 |
| CD4, no. (%) | ||||
| Current < 200; nadir < 200 | 34 (15) | 7 (11) | 27 (16) | 0.530 |
| Current ≥ 200, nadir < 200 | 101(43) | 29 (45) | 72 (43) | |
| Current ≥ 200, nadir ≥ 200 | 95 (41) | 27 (42) | 68 (40) | |
| Plasma HIV RNA detectable, no. (%) | ||||
| All individuals | 121(52) | 31 (49) | 90 (53) | 0.558 |
| ON CART**, no. (%) | 61 (26) | 19 (30) | 42 (36) | 0.505 |
| OFF CART**, no. (%) | 60 (26) | 12 (19) | 48 (28) | 0.179 |
| Cerebrospinal fluid HIV RNA detectable, no. (%) | ||||
| All individuals | 68 (30) | 16 (25) | 52 (31) | 0.423 |
| ON CART,** no. (%) | 24 (10) | 7 (11) | 17 (14) | 0.813 |
| OFF CART,** no. (%) | 44 (19) | 9 (14) | 35 (21) | 0.268 |
| CART** use, no. (%) | ||||
| Current | 170 (73) | 52 (81) | 118 (70) | 0.107 |
| Past | 37 (16) | 9 (14) | 28 (17) | |
| Never | 26 (11) | 3 (5) | 23 (14) | |
| D-drug,** no. (%) | ||||
| Current | 39 (17) | 11 (17) | 28 (17) | 0.230 |
| Past | 87 (37) | 29 (45) | 58 (34) | |
| Never | 107 (46) | 24 (38) | 83 (50) | |
| Beck depression inventory II, mean (SD) | 12 (11) | 16 (11) | 11 (11) | 0.001* |
| Lifetime major depressive disorder,*** no. (%) | 51 (22) | 21 (33) | 30 (18) | 0.020* |
| History of inhalant abuse, no. (%) | 5 (2) | 3 (5) | 2 (1) | 0.129 |
| History of methamphetamine abuse, no. (%) | 8 (3) | 2 (3) | 6 (4) | 1.000 |
| Global deficit score, mean (SD) | 0.4 (0.4) | 0.4 (0.4) | 0.4 (0.5) | 0.991 |
*
DNP and non-DNP characteristics are statistically different.
**
D-drug = dideoxynucleoside reverse transcriptase inhibitors; CART = combination antiretroviral therapy.
***
Major depressive disorder = Meets DSM-IV criteria for a major depressive episode within the last 30 days.