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. 2016 Nov 14;72(2):574–581. doi: 10.1093/jac/dkw423

Table 2.

Adherence to the SHEA-IDSA recommendations for the initial treatment of CDI stratified by severity of disease

Treatment adherence according to disease severity (n) Under-treated Appropriately treated Over-treated
Mild-moderate (136) 1 (0.7%)a 81 (59.6%) 54 (39.7%)b
Severe (48) 15 (31.2%)c 27 (56.3%) 6 (12.5%)d
Severe-complicated (46) 30 (65.2%)e 16 (34.8%) 0 (0%)
Total (230) 46 (20%) 124 (54%) 60 (26%)

aReason for under-treatment was short duration (<10 days) of therapy with metronidazole.

bThe most common finding of over-treatment in the mild-moderate CDI group was use of oral vancomycin (52 of 54).

cThe most common finding of under-treatment in the severe CDI group was use of metronidazole instead of vancomycin (14 of 15).

dThe most common finding of over-treatment in the severe CDI group was use of a combination of metronidazole and vancomycin (four of six).

eThe most common findings of under-treatment in the severe-complicated CDI group was use of metronidazole alone (5 of 30) or use of vancomycin alone without intravenous metronidazole (8 of 30) or use of vancomycin at 125 mg every 6 h instead of at 500 mg every 6 h in combination with intravenous metronidazole (17 of 30).