Table 2.
Treatment adherence according to disease severity (n) | Under-treated | Appropriately treated | Over-treated |
---|---|---|---|
Mild-moderate (136) | 1 (0.7%)a | 81 (59.6%) | 54 (39.7%)b |
Severe (48) | 15 (31.2%)c | 27 (56.3%) | 6 (12.5%)d |
Severe-complicated (46) | 30 (65.2%)e | 16 (34.8%) | 0 (0%) |
Total (230) | 46 (20%) | 124 (54%) | 60 (26%) |
aReason for under-treatment was short duration (<10 days) of therapy with metronidazole.
bThe most common finding of over-treatment in the mild-moderate CDI group was use of oral vancomycin (52 of 54).
cThe most common finding of under-treatment in the severe CDI group was use of metronidazole instead of vancomycin (14 of 15).
dThe most common finding of over-treatment in the severe CDI group was use of a combination of metronidazole and vancomycin (four of six).
eThe most common findings of under-treatment in the severe-complicated CDI group was use of metronidazole alone (5 of 30) or use of vancomycin alone without intravenous metronidazole (8 of 30) or use of vancomycin at 125 mg every 6 h instead of at 500 mg every 6 h in combination with intravenous metronidazole (17 of 30).