Table 2.
Comparison | Sample size | No. | Test of association | Heterogeneity | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Case | Control | Studies | OR (95% CI) | Z | P value | Model | c2 | P value | I2 (%) | ||
| |||||||||||
AA (A) vs AG+GG (G) | Overall | 2846 | 3508 | 20 | 1.32(1.18–1.47) | 4.80 | <.001 | F | 24.45 | .18 | 22.0 |
AA (A) vs AG+GG (G) | Asian | 1865 | 2069 | 12 | 1.28(1.10–1.49) | 3.22 | .001 | F | 13.25 | .28 | 17.0 |
AA (A) vs AG+GG (G) | Caucasian | 981 | 1439 | 8 | 1.37(1.15–1.62) | 3.62 | <.001 | F | 10.80 | .15 | 35.0 |
A vs G | Male | 1038 | 1143 | 12 | 1.49(1.22–1.81) | 3.97 | <.001 | F | 4.29 | .96 | 0 |
AA vs AG+GG | Female | 764 | 970 | 12 | 1.32(1.06–1.64) | 2.45 | .01 | F | 6.99 | .80 | 0 |
F: Fixed-effects model.