Figure 3.
Fine-mapping examples. Examples from studies of C-reactive protein (104), serum uric acid (129), serum lipids (116), and T2D (53) showing how smaller haplotype blocks in African ancestry populations helped refine genome-wide significant loci. Data are shown for fine-mapping analyses conducted in sub-Saharan Africans from Nigeria, Ghana and Kenya (AADM) and in AA from the Washington DC region in the United States (HUFS).