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. 2017 Apr 18;40(6):zsx055. doi: 10.1093/sleep/zsx055

Table 5.

ANOVA-based heritability estimates of heart rate response to arousal measures in MZ and DZ twinsa.

Measures Within pair average value Total variance Heritability estimate
F-testb T-testc F-testb
p p p H2 pd Type
Arousal index .530 .519 .730 0.307 .129 WP
Average arousal duration .416 .395 .798 0.460 .117 WP
Average arousal intensity scale .535 .333 .507 1.127 <.001 WP
Slope of ΔHR per arousal intensity .124 .074 .065 −0.605 .898 AmCo
Arousal intensity threshold of ΔHR .170 .702 .831 1.237 .002 WP
Average ΔHR .293 .066 .074 −0.248 .695 AmCo
ΔHR at arousal intensity scale 4 .821 .090 .600 0.240 .165 WP
ΔHR at arousal intensity scale 5 .447 .063 .334 0.085 .348 WP
ΔHR at arousal intensity scale 8 .168 .051 .117 −0.662 .911 AmCo

aHeritability estimates using analysis of variance (ANOVA)-based variance formulas for within pairs (WP) or among component (AmCo) heritability. The WP estimate is most valid when the total variance F-test has a p>.20, and calculated as H2 = [2 • (MSWDZ - MSWMZ)] / [(MSAMZ + MSWDZ + MSADZ + MSWMZ)/4]. The AmCo estimate is valid when the total variance F-test has a p<.20, and calculated H2 = [(MSAMZ - MSADZ) + (MSWDZ - MSWMZ)] / [(MSAMZ + MSWDZ + MSADZ + MSWMZ)/4]28,29.

bF-test p-value comparing variability in indicated measure between MZ and DZ twins.

cT-test p-value comparing within pair average values in indicated measure between MZ and DZ twins.

done-sided p-values based on F-tests of significance for heritability estimate, using F-ratio = MSWDZ / MSWMZ for WP heritability estimates and an F-ratio = (MSAMZ + MSWDZ) / (MSADZ + MSWMZ) for AmCo heritability estimates. Abbreviations: H2: broad-sense heritability, ΔHR: heart rate response to arousal, WP: within pairs heritability estimate, AmCo: among component heritability estimate.