Resting-state functional network alteration assessed using ICA. Panels (
A-I
) and (
B-I
) represent the extracted components relevant to dystonia across all patients and healthy participants (
A-I
for the sensorimotor and
B-I
for frontoparietal independent components). For each component, voxel-based inferential statistics were used to compare (
II
) all patients vs. healthy participants, and (
III
) TSD vs. NTSD groups. Statistical maps are superimposed on axial and sagittal sections of a standard brain in Talairach–Tournoux space. The color bars represent
Z
-scores for independent components and
t
scores for group statistical comparisons (
P
≤ 0.05, FWE-corrected). The corresponding bar graphs of the group-averaged resting-state connectivity in the significant clusters are shown in the bottom row of the figure. SMC, sensorimotor cortex; STG, superior temporal gyrus; INS, insula; SSC, somatosensory cortex; PFC, prefrontal cortex; MTG, middle temporal gyrus; IPC, inferior parietal cortex.