Figure 1.

Schematic presentation of the experimental design. Mice were injected with saline or eszopiclone 6 hours after the light onset (ZT6). In groups 3 and 4, mice were sleep deprived from ZT0 to ZT6 and then allowed a recovery sleep opportunity from ZT6 to approximately ZT9. Brain tissue samples were taken from all mice at 9 hours after light onset (ZT9). The black and white bars at the base of the schematic represent the dark and light phases of the light/dark cycle.