Table 2. Stratified analyses of the MTR gene rs1805087 A2756G polymorphism on prostate cancer risk.
| Variables | N | Cases/ | G-allele vs. A-allele | GG vs. AA | GA vs. AA | GG+GA vs. AA | GG vs. GA+AA | ||||
| Controls | OR(95%CI) Phetera P I2 | OR(95%CI) Phetera P I2 | OR(95%CI) Phetera P I2 | OR(95%CI) Phetera P I2 | OR(95%CI) Phetera P I2 | ||||||
| Total | 7 | 2921/3095 | 1.16(1.04-1.30) 0.078 0.008 47.2 | 1.33(0.93-1.92) 0.280 0.119 19.6 | 1.17(1.02-1.33) 0.229 0.020 26.1 | 1.18(1.04-1.34) 0.102 0.010 43.4 | 1.24(0.86-1.77) 0.493 0.246 0 | ||||
| Ethnicity | |||||||||||
| Caucasian | 3 | 683/639 | 1.03(0.85-1.24)0.897 0.792 0 | 0.86(0.50-1.46) 0.812 0.569 0 | 1.11(0.88-1.40) 0.983 0.392 0 | 1.07(0.86-1.35) 0.962 0.535 0 | 0.83(0.49-1.40) 0.810 0.478 0 | ||||
| Asian | 3 | 2134/2346 | 1.22(1.06-1.40) 0.050 0.006 66.6 | 1.93(1.14-3.26) 0.390 0.014 0 | 1.31(0.84-2.05) 0.044 0.233 68.0 | 1.38(0.87-2.20) 0.024 0.174 73.2 | 1.72(1.02-2.89) 0.767 0.041 0 | ||||
| South America | 1 | 104/110 | 2.77(1.05-7.29) - 0.039 - | 3.42(0.35-33.49) - 0.290 - | 2.57(0.77-8.02) - 0.127 - | 2.74(0.93-8.07) - 0.067 - | 3.24(0.33-31.63) - 0.312 - | ||||
| Source of control | |||||||||||
| Population-based | 2 | 474/395 | 1.48(0.55-4.00) 0.042 0.439 75.7 | 0.87(0.44-1.73) 0.206 0.699 37.4 | 1.16(0.85-1.60) 0.182 0.344 43.9 | 1.13(0.84-1.53) 0.092 0.417 64.8 | 0.84(0.43-1.65) 0.213 0.615 35.6 | ||||
| Hospital-based | 5 | 2447/2700 | 1.19(1.05-1.34) 0.159 0.007 39.4 | 1.58(1.03-2.42) 0.444 0.038 0 | 1.17(1.01-1.35) 0.175 0.033 36.9 | 1.19(1.04-1.36) 0.105 0.014 47.8 | 1.44(0.94-2.20) 0.734 0.093 0 | ||||
a P value of Q-test for heterogeneity test(Pheter).