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. 2018 Jul 18;10(7):1609–1626. doi: 10.18632/aging.101496

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Copyright © 2018 Cho et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY) 3.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The common gene expression changes with aging in suprapubic and lower leg tissues. (A) Module trait relationship of constructed modules from lower leg. The statistically significant modules were marked with asterisk. The correlation values and Bonferroni-corrected P-values (in the bracket) were marked. (B) Pathway enrichment analysis of tan module. Top 10 the most enriched pathways were used. (C) The changes in gene expression level of three genes that play a role in heparan sulfate proteoglycan biosynthetic process in both tissues were shown. (D) Heatmap displays the expression level of nine genes that play a role in wound healing process in both tissues.