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Simulated roxithromycin total and free exposure on day 7 of treatment with approved dosing regimens (150 mg twice daily or 300 mg daily; black) or higher dose regimens (450 mg daily or 300 mg twice daily; grey) (n = 1000 individuals). The central box line represents the median, with the box ends representing the 25th and 75th percentiles. The bars extend to the 5th and 95th percentiles. BD, twice daily; D, daily.
