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. 2017 Feb 8;26(8):1458–1464. doi: 10.1093/hmg/ddx048

Figure 3.

Figure 3

α7 integrin expression is decreased in Ptrh2 null skeletal muscle. (A) Immunofluorescence and Western blot (B) of the α7 integrin showed reduced protein levels in gastrocnemius muscle in Pthr2 null (Ptrh2-/-) mice at P7 compared to WT littermate controls (n = 3 per genotype for immunoblots and immunofluorescence; bar 10 μm). (C) Western blot analysis of the gastrocnemius muscle lysate indicated that Ptrh2 and pAKT/tAKT are decreased in Ptrh2-/- and α7-/-mice compared to WT (n = 3 per genotype for immunoblots and immunofluorescence; **P<0.001). Data shown in A–C are representative of three independent experiments.