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. 2017 Jan 10;140(3):669–683. doi: 10.1093/brain/aww342

Figure 2.

Figure 2

Radioligand binding assay to identify binding targets of clemizole. Clemizole was subjected to radioligand binding assay against 132 targets. The functional agonist activity of clemizole against 67 targets is shown. Compound binding was calculated as % inhibition of the binding of a radioactively-labelled ligand specific for each target. Inhibition or stimulation higher than 50% and are represented in yellow and are considered to represent significant effects of clemizole.