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ΔNLS-TDP-43 associates translational machinery. (A) The SH-SY5Y cells overexpressing Myc-ΔNLS-TDP-43 showed co-localization in cytoplasm with RACK1 and rpS6, which was more pronounced in ΔNLS-TDP-43 cytoplasmic inclusions indicated by arrows. Scale bar = 10 µm. (B) RACK1 and rpS6 proteins were eluted with ΔNLS-TDP-43 purified by Myc immunoprecipitation assay from SH-SY5Y cells overexpressing Myc-ΔNLS-TDP-43 protein.
