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. 2017 Feb 21;26(11):1979–1991. doi: 10.1093/hmg/ddx065

Figure 5.

Figure 5

Lack of AnxA2 reduces fatty replacement of dysferlinopathic muscles. Gastrocnemius muscle from 12-month-old WT, A2, B6A/J and B6A/JA2 mice were stained with (A) haematoxylin & eosin, (B) Oil Red O and (C) immunostained for Perilipin1 (red). Scale = 200 µm for A & B and 100 µm for C. (D) Using images of whole muscle section the number of perlilipin1 stained foci were quantified (n = 3 animals each). Blue: DAPI, Green: Wheat germ Agglutinin (Alexa Fluor 488 conjugate), and Red: Perilipin1 (Alexa fluor 568 conjugate).The plots represent mean ± SEM. *P ≤ 0.05 compared to WT by Kruskal Wallis test.