TABLE 1.
Candidate Quantitative Trait Genes Identified by Merge Analysis
| Gene Symbol | Gene Name | Human Orthologue | Liver Expression | Biological Relevance |
|---|---|---|---|---|
| 4930438E09Rik | RIKEN cDNA 4930438E09 gene | − | NA | NA |
| Adam2 | A disintegrin and metallopeptidase domain 2 | + | − | NA |
| Adam28 | A disintegrin and metallopeptidase domain 28 | + | − | NA |
| Adam7 | A disintegrin and metallopeptidase domain 7 | + | − | NA |
| Adra1a | Adrenoceptor alpha 1A | + | + | − |
| Bnip3l | BCL2/adenovirus E1B 19kDa interacting protein 3-like | + | + | − |
| Cdca2 | Cell division cycle associated 2 | + | − | NA |
| Dock5 | Dedicator of cytokinesis 5 | + | + | − |
| Dpysl2 | Dihydropyrimidinase-like 2 | + | + | − |
| Ebf2 | Early B-cell factor 2 | + | − | NA |
| Elp3 | Elongator acetyltransferase complex subunit 3 | + | + | − |
| Ephx2a | Epoxide hydrolase 2, cytoplasmic | + | + | + |
| Fbxo16 | F-box protein 16 | + | + | − |
| Fzd3 | frizzled homolog 3 | + | + | − |
| Gm10032 | Predicted gene 10032 | − | NA | NA |
| Gm10860 | Predicted gene 10860 | − | NA | NA |
| Gm20667 | Predicted gene 20667 | − | NA | NA |
| Gm23899 | Predicted gene 23899 | − | NA | NA |
| Gm24258 | Predicted gene 24258 | − | NA | NA |
| Gm27647 | Predicted gene 27647 | − | NA | NA |
| Gm6878 | Predicted gene 6878 | − | NA | NA |
| Kctd9 | Potassium channel tetramerization domain containing 9 | + | + | − |
| Mir6539 | MicroRNA 6539 | – | NA | NA |
| Nuggc | Nuclear GTPase, germinal center associated | + | + | – |
| Pnma2 | Paraneoplastic antigen MA2 | + | − | NA |
| Pnoc | Prepronociceptin | + | − | NA |
| Ppp2r2a | Protein phosphatase 2, regulatory subunit B, alpha | + | + | − |
| Ptk2b | PTK2 protein tyrosine kinase 2 beta | + | + | − |
| Scara3a | Scavenger receptor class A, member 3 | + | + | + |
| Scara5 | Scavenger receptor class A, member 5 | + | + | − |
| Spata13 | Spermatogenesis associated 13 | + | + | − |
| Stmn4 | Stathmin-like 4 | + | − | NA |
| Zfp395a | Zinc finger protein 395 | + | + | + |
a
Indicates priority candidate QTGs based on meeting all 3 criteria: human ortholog, liver expression, and biological relevance.