Figure 6.
Prkg1 knockout offers long-term rescue of Cngb1-/- rods. Light micrograph of retinal sections from Cngb1-/- and Cngb1-/-Prkg1-/- littermates at 4- (A) and 5- months (B) of age. The remaining ONL is highlighted by the vertical bar at the right side of each panel. Scale bar = 20 μm. (C) Retinal section from a 5 month-old Cngb1-/-Prkg1-/- mouse stained with peanut agglutinin (PNA), a cone marker. PNA staining is seen primarily in the central-inferior region of the retina (white arrow). The inset shows a higher magnification from the boxed region. S, superior; I, inferior.
