TABLE 2.

Effect of Prenatal DEHP Exposure on Sperm Morphological Abnormalities

Parameters	Control	200 µg/kg/day	500 mg/kg/day	750 mg/kg/day
Normal sperm (%)	76.43 ± 1.69	59.13 ± 2.32 *	45.85 ± 2.01*	19.52 ± 0.26 *
Total sperm abnormalities (%)	23.54 ± 0.66	41.09 ± 3.92 *	54.27 ± 0.99*	80.55 ± 0.11*
Head abnormality (%)	9.13 ± 1.89	18.56 ± 1.55*	25.13 ± 2.11*	31.90 ±1.70*
Neck and Midpiece abnormality (%)	7.33 ± 0.54	11.18 ± 2.42	15.21 ± 0.89*	23.51 ± 2.01*
Tail abnormality (%)	6.01 ± 0.81	9.31 ± 1.71	11.34 ± 0.67	21.88 ± 0.44*
Double tail and head (%)	1.62 ± 1.10	2.01 ± 1.12	2.11 ± 1.45	3.30 ± 1.99*

Count 100 sperm from each group. Showed percent of normal sperm, percent of total sperm abnormalities, percent of sperm with head abnormalities, percent of sperm with neck and midpiece abnormalities, percent of sperm with tail abnormalities and percent of double tail and head sperm. Asterisks indicate P ≤ .05 compared with control group, data are mean ± SEM (n = 4–7 per treatment group) except 20µg/kg/day group all of mice was dead at 22 months of age.