Table 4.
Genes regulated by Dex only in sensitive CEM clones, compared with regulation by Dex or Dex+Compound E in CUTLL1 cells
| C1-6 and C7-14 | CUTLL1 | CUTLL1 |
|---|---|---|
| A. Decreased by Dex | Dex | Compound E + Dex |
| CELSR3 | + | NR |
| TSR1 | NR | + |
| NOP16 | NR | + |
| NKX2-5 | NR | + |
| PRMT3 | NR | + |
| FAM216A | NR | + |
| CCDC86 | NR | + |
| HES 1 | NR | + |
| BYSL | NR | + |
| APOE | NR | + |
| B. Increased by Dex | Dex | Compound E + Dex |
| DFNA5 | + | NR |
| PTK2B | + | + |
| NR3C1 (GR) | + | + |
| MAP1A | + | + |
| RCA1 | + | + |
| BTG1,2 | + | + |
| SOCS 1 | + | + |
| METTL7A | + | + |
| TUBA4A | NR | + |
| SLA | NR | + |
| BIRC 3 | NR | + |
| RHOBTB3 | NR | + |
| CD53 | NR | + |
| BCL2L11 | NR | + |
| TGFBR2 | NR | + |
| SRGN | NR | + |
| CD69 | NR | + |
| WFS1 | NR | + |
Criteria for inclusion in C1-6, C7-14 gene list: decreased > 2 fold; increased > 2.5 fold (Webb, Miller, Johnson, et al. 2003); in CUTLL1 cells: See (Real and Fernando 2008 dataset citation). Symbols: NR, not regulated, “+”, regulated with statistical significance.