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NOTCH pathway genes regulated by Dex after 3 hr in CEM C7-14 or C1-15 cells
| GENE | FOLD CHANGE (p value) | Function | |
|---|---|---|---|
| C7-14 cells | C1-15 cells | ||
| NOTCH | −1.4 (p<0.006) | NS* | Signal transduction |
| JAG1 | +1.97 (p<0.015) | NS | Notch binding, activation |
| NFKBIA | +1.6 (p<0.02) | NS | Decrease NFKB activity |
| ADAM17 | −1.25 (p<0.005) | NS | Cleaves, activates NOTCH |
| SBNO1 | −1.7 (p<0.017) | NS | Homolog, Drosophila |
| ASCL1 | −1.25 (p<0.04) | NS | Transcription factor |
| SBNO1 | NS | +1.17 (p<0.02) | homolog |
NS = not statistically significant.
