Tissue expression of NOV and EET agonist effect on plasma and kidney NOV levels and plasma Angiotensin 2. (A) The mRNA expression of NOV in kidney, visceral fat, and peri-renal fat. (B) Representative western blots, densitometry analysis of NOV in plasma of db/db control mice, db/db treated with EET-A mice, and PGC-1α- deficient. (C) Representative western blots, densitometry analysis of NOV in Kidney of db/db control mice, db/db treated with EET-A mice, and PGC-1a-deficient. (D) mRNA expression of NOV in plasma of db/db control mice, db/db treated with EET-A mice, and PGC-1α-deficient. (E) Plasma Angiotensin II. Results are means ± SE, n=6, *p<0.05 vs db/db control, # p<0.05 vs db/db mice treated with EETA /.