TABLE 3.
Cytological features helping the diagnosis of melanomas over Clark’s nevi
| Cytological feature | Melanoma (n = 84) (%) | Clark’s nevi (n = 100) (%) | Chi-square | P-value |
|---|---|---|---|---|
| Pleomorphism with enlarged nuclei | 93 | 3 | 149.5 | <.001 |
| Notching | 86 | 1 | 136.8 | <.001 |
| Multiple nucleoli | 74 | 0 | 111.3 | <.001 |
| Peppered moth nuclear pattern | 74 | 0 | 111.3 | <.001 |
| Flattening of adjacent nuclei | 91 | 26 | 76.8 | <.001 |
| Mitotic figures | 39 | 0 | 47.8 | <.001 |
| Molding | 43 | 2 | 46.5 | <.001 |
| Abnormal mitotic figures | 24 | 0 | 26.7 | <.001 |
| Absent/ inconspicuous nucleoli |
67 | 94 | 22.6 | <.001 |
| Single prominent nucleolus | 20 | 5 | 10.07 | .002 |
| Vesicular nuclei with single rounded nucleolus | 7 | 0 | Fisher’s exact |
.008 |