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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: J Cutan Pathol. 2017 Dec 28;45(3):204–207. doi: 10.1111/cup.13085

TABLE 4.

Sensitivity, specificity and overall accuracy of cytological features found to help diagnosing melanoma over Clark’s nevi

Cytological feature Specificity
(%)
Sensitivity
(%)
Overall accuracy (%)
Pleomorphism with 97 92.9 95.1
enlarged nuclei
Notching 99 85.7 92.9
Multiple nucleoli 100 73.8 88
Peppered moth 100 73.8 88
nuclear pattern
Flattening of adjacent 74 90.5 81.5
Nuclei
Mitotic figures 100 39.3 72.2
Molding 98 42.9 72.8
Abnormal mitotic figures 100 23.8 65.2
Single prominent nucleolus 95 20.2 60.8
Vesicular nuclei with single rounded nucleolus 100 7.1 57.6