TABLE 3.
Multivariable Logistic Regression Analyses to Predict the Risk of Postvaccination Presyncope Defined by the Primary and Restrictive Outcomes
| Primary Outcomea | Restrictive | |
|---|---|---|
| aOR (95% CI) | Outcomea aOR | |
| (95% CI) | ||
| Age, y | ||
| <15 | 2.27 (1.79–2.88) | 2.84 (1.83–4.39) |
| ≥15 | Reference | Reference |
| Sex | ||
| Male | Reference | Reference |
| Female | 1.20 (0.97–1.48) | 1.03 (0.71–1.51) |
| Passed out or nearly passed out from shot or blood draw in the past 5 y |
||
| No | Reference | Reference |
| Yes | 1.91 (1.27–2.87) | 2.70 (1.48–4.91) |
| Hunger or thirst | ||
| Not at all or a little bit | Reference | Reference |
| Very | 1.15 (0.90–1.47) | 1.46 (0.97–2.19) |
| Prevaccination anxiety | ||
| None or slight | Reference | Reference |
| Mild, moderate, or severe | 1.86 (1.45–2.38) | 2.77 (1.82–4.20) |
| No. of injectable vaccines | ||
| 1 | Reference | Reference |
| >1 | 1.53 (1.24–1.89) | 1.95 (1.33–2.86) |
| Receipt of HPV vaccine | ||
| No | Reference | Reference |
| Yes | 1.03 (0.83–1.28) | 1.00 (0.68–1.48) |
| Pain intensity | ||
| 0–1 | Reference | Reference |
| 2–5 | 2.96 (2.21–3.98) | 4.96 (3.34–7.36) |
| Group | ||
| Control | Reference | Reference |
| Intervention | 0.92 (0.75–1.13) | 0.84 (0.58–1.21) |
The outcomes were adjusted for each listed variable and enrollment center. aOR, adjusted odds ratio.
a
The primary outcome is “a little bit” or more in response to any of the 12 items on the presyncope instrument. The restrictive outcome is “somewhat” or more in response to any of the 12 items on the presyncope instrument.