Table 1.
Patient and disease characteristics among all nonsurgical patients (n = 448).
|
Characteristic |
Patients, No. (%) |
| Median age at diagnosis, y | 68 (range, 20-92) |
| Sex | |
| Male | 371 (83) |
| Female | 77 (17) |
| Histology | |
| Adenocarcinoma | 336 (75) |
| Squamous cell carcinoma | 112 (25) |
| Stage | |
| I | 15 (3) |
| IIA | 124 (28) |
| IIB | 23 (5) |
| III | 264 (59) |
| IVA | 22 (5) |
| Tumor location | |
| Upper thoracic esophagus | 28 (6) |
| Middle thoracic esophagus | 77 (17) |
| Lower thoracic esophagus | 343 (77) |
| Karnofsky performance status | |
| 100 | 19 (4) |
| 90 | 165 (37) |
| 80 | 218 (49) |
| 70 | 46 (10) |
| Induction chemotherapy | |
| Yes | 132 (29) |
| No | 316 (71) |
| Radiation Modality | |
| PBT | 165 (37) |
| IMRT | 283 (63) |
| Median PTV (cm3) | 589 (range, 93-3125) |
Abbreviations: PBT, proton beam therapy; IMRT, intensity-modulated radiation therapy, PTV, planning treatment volume.