Skip to main content
. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Curr Opin HIV AIDS. 2018 Jul;13(4):359–365. doi: 10.1097/COH.0000000000000472

Figure 3.

Figure 3

HIV-1 CA binding sites for three antiviral compounds and one peptide. C1, PF74, and CAP-1 occupy distinct sites on the NTD; the stapled peptide ligand NYAD-13, an analogue of CAI, binds to the CTD dimer interface. This figure illustrates several known binding sites for capsid-targeting HIV inhibitors and is a composite generated using the CA monomer from 4xfz.pdb [1] with the ligand coordinates aligned from 2jpr.pdb [18], 4e91.pdb [19], and 2l6e.pdb [20].