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. Author manuscript; available in PMC: 2018 Aug 3.
Published in final edited form as: Cell Rep. 2018 Apr 3;23(1):313–326.e5. doi: 10.1016/j.celrep.2018.03.075

Figure 1. Comparison of RCC Histologic Subtypes.

Figure 1

(A) Heatmap representation of chromosomal copy number and RNA expression profiles between the different histologic RCC subtypes. Chromosomal copy number data are ordered by chromosomal arm in descending order (red, gain; blue, loss). The relative RNA expression was assessed for the most variable probes within the complete RCC cohort for either mRNA (n = 500), miRNA (n = 249), or lncRNA (n = 178) (red, increased; blue, decreased). RCC samples were arrayed left to right based on histologic subtype (ccRCC, green; type 1 PRCC, light blue; type 2 PRCC, orange; unclassified [Unc.] PRCC, gray; CIMP-RCC, red; ChRCC, purple), then tumor stage (stage I, light green; stage II, yellow; stage III, orange; stage IV, red), and then vital status (alive, white; deceased, black). (B) Percentage of chromosomal copy number alterations between the different histologic RCC subtypes. (C) Differences in patient overall survival between the different histologic RCC subtypes (log-rank p value).