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. Author manuscript; available in PMC: 2018 Aug 3.
Published in final edited form as: Cell Rep. 2018 Apr 3;23(1):313–326.e5. doi: 10.1016/j.celrep.2018.03.075

Figure 4. RCC Histologic Subtypes Associate with Specific mRNA Signatures.

Figure 4

(A) Heatmap representation of the comparison of mRNA expression signatures for major cellular processes between the different histologic RCC subtypes (ccRCC, green; type 1 PRCC, light blue; type 2 PRCC, orange; Unc. PRCC, gray; CIMP-RCC, red; ChRCC, purple). Tumor stage (stage I, light green; stage II, yellow; stage III, orange; stage IV, red) and vital status (alive, white; deceased, black) are indicated above the heatmap. (B) Heatmap representation showing the relationship between gene expression modules and clinical features. Red heatmap shading indicates a positive correlation between a gene module and a clinical feature and blue heatmap shading represents a negative correlation.