(A) Heatmap representation of the comparison of mRNA expression signatures for major cellular processes between the different histologic RCC subtypes (ccRCC, green; type 1 PRCC, light blue; type 2 PRCC, orange; Unc. PRCC, gray; CIMP-RCC, red; ChRCC, purple). Tumor stage (stage I, light green; stage II, yellow; stage III, orange; stage IV, red) and vital status (alive, white; deceased, black) are indicated above the heatmap. (B) Heatmap representation showing the relationship between gene expression modules and clinical features. Red heatmap shading indicates a positive correlation between a gene module and a clinical feature and blue heatmap shading represents a negative correlation.