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. 2018 Aug 3;13(8):e0201799. doi: 10.1371/journal.pone.0201799

Table 1. Characteristics of the patients with and without RA.

Characteristic RA
(n = 71)
Non-RA
(n = 1478)
p value
Age (years) 71.0 ± 8.9a 66.9 ± 17.1 <0.001
≥65 years 53 (74.6) 956 (64.7) 0.097
Female sex 39 (54.9) 451 (30.5) <0.001
Smokers 29 (40.8) 918 (62.1) <0.001
HCAP 23 (32.4) 484 (32.7) 1.000
Comorbidity
 None 10 (14.1) 339 (22.9) 0.008
 Pulmonary disease 51 (71.8) 772 (52.2) 0.001
  COPD 12 (16.9) 324 (21.9) 0.377
  Asthma 1 (1.4) 149 (10.1) 0.012
  Bronchiectasis 9 (12.7) 91 (6.2) 0.043
  Nontuberculous mycobacteriosis 10 (14.1) 65 (4.4) 0.002
  Old pulmonary tuberculosis 3 (4.2) 105 (7.1) 0.477
  Chronic pulmonary aspergillosis 1 (1.4) 25 (1.7) 1.000
  Interstitial pneumonia 21 (29.6) 85 (5.8) <0.001
  Post lung cancer operation 1 (1.4) 57 (3.9) 0.517
  Other pulmonary diseaseb 12 (16.9) 56 (3.8) <0.001
 Systemic disease 33 (46.5) 655 (44.3) 0.716
Steroid or immunosuppressant 46 (64.8) 87 (5.9) <0.001
Severe 7 (9.9) 218 (14.7) 0.303
Mortality 8 (11.3) 74 (5.0) 0.050

RA, rheumatoid arthritis; HCAP, healthcare-associated pneumonia; COPD, chronic obstructive pulmonary disease.

aData are presented as means ± standard deviation or n (%).

b“Other pulmonary disease” includes the following incidences of each disease: bronchiolitis (n = 6), chronic eosinophilic pneumonia (n = 2), and others (n = 5) in the RA patients, and pneumoconiosis (n = 13), sarcoidosis (n = 9), chronic empyema (n = 8), pulmonary thromboembolism (n = 6), asbestos pleuritis (n = 4), pulmonary hypertension, alveolar proteinosis (n = 3 each), and others (n = 10) in the non-RA patients. Some patients had more than one comorbidity.