Table 2. Characteristics of the patients with RA.
| Characteristic | Pulmonary comorbidity | Therapeutic agents for RA | Severity | Non-Survivors | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Present (n = 51) |
None (n = 20) |
p value | Biological agent and/or MTX (n = 18) |
Others (n = 53) |
p value | Severe (n = 7) |
Non-severe (n = 64) |
p value | Non-survivors (n = 8) |
Survivors (n = 63) |
p value | |
| Age (years) | 73.0 ± 8.1a | 66.1 ± 9.1 | 0.002 | 68.1 ± 10.0 | 72.0 ± 8.3 | 0.100 | 74.4 ± 8.4 | 70.7 ± 8.9 | 0.289 | 73.9 ± 7.4 | 70.7 ± 9.0 | 0.339 |
| Female sex | 24 (47.1) | 15 (75.0) | 0.038 | 10 (55.6) | 29 (54.7) | 1.000 | 2 (28.6) | 37 (57.8) | 0.231 | 4 (50.0) | 35 (55.6) | 1.000 |
| Smokers | 24 (47.1) | 5 (25.0) | 0.112 | 7 (38.9) | 22 (41.5) | 1.000 | 4 (57.1) | 25 (39.1) | 0.433 | 2 (25.0) | 27 (42.9) | 0.458 |
| HCAP | 18 (35.3) | 5 (25.0) | 0.574 | 5 (27.8) | 18 (34.0) | 0.774 | 1 (14.3) | 22 (34.4) | 0.415 | 1 (12.5) | 22 (34.9) | 0.261 |
| Steroid or immunosuppressant | 31 (60.8) | 15 (75.0) | 0.287 | 18 (100.0) | 28 (52.8) | <0.001 | 2 (28.6) | 44 (68.8) | 0.088 | 2 (25.0) | 44 (69.8) | 0.019 |
| Comorbidity | ||||||||||||
| None | 0 (0.0) | 10 (50.0) | <0.001 | 5 (27.8) | 5 (9.4) | 0.036 | 2 (28.6) | 8 (12.5) | 0.687 | 0 (0.0) | 10 (15.9) | 0.254 |
| Pulmonary disease | 51 (100.0) | 0 (0.0) | <0.001 | 9 (50.0) | 42 (79.2) | 0.031 | 4 (57.1) | 47 (73.4) | 0.394 | 8 (100.0) | 43 (68.3) | 0.095 |
| Systemic disease | 23 (45.1) | 10 (50.0) | 0.794 | 6 (33.3) | 27 (50.9) | 0.275 | 3 (42.9) | 30 (46.9) | 1.000 | 5 (62.5) | 28 (44.4) | 0.459 |
| Severe | 4 (7.8) | 3 (15.0) | 0.394 | 2 (11.1) | 5 (9.4) | 1.000 | 7 (100.0) | 0 (0.0) | <0.001 | 3 (37.5) | 4 (6.3) | 0.027 |
| Mortality | 8 (15.7) | 0 (0.0) | 0.095 | 0 (0.0) | 8 (15.1) | 0.105 | 3 (42.9) | 5 (7.8) | 0.027 | 8 (100.0) | 0 (0.0) | <0.001 |
RA, rheumatoid arthritis; HCAP, healthcare-associated pneumonia.
aData are presented as means ± standard deviation or n (%).