Fig 3. Tensor based morphometry comparison between SPF and GF mice.

Animal numbers: SPF (n = 5 for both females and males) and GF (n = 5 for both females and males) mice at 12 weeks of age. No significant difference was detected at four weeks of age with the same number of animals in each group. The pseudo-colored statistical parametric map is overlaid on a gray scale template. Statistically significant regional volume expansion in olfactory bulbs and prefrontal cortex in GF group is indicated by pseudo-colored voxels in red-yellow scale. Color bar indicates corrected p-values range and p value of <0.05 was considered statistically significant.