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. 2018 Jul 24;12(7):e0006679. doi: 10.1371/journal.pntd.0006679

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© 2018 Zoltner et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 5 — Presented is a model that is consistent with all available data. PABP1 preferentially binds to a subset of mRNAs of mainly small size, while PABP2 binds to the larger set of bulk mRNAs. The basal translation initiation factors eIF4E4 and eIF4G3 associate with all mRNA targets, while eIF4E5 and eIF4G1 are specific for (a subset of?) PABP2 target mRNAs. All PABP interacting partners are shown with thick lines (>10 fold enrichment) or thin lines (>2 fold enrichment).