TABLE 1.
Fatty acid composition of plasma lipids in dietary n-3 PUFA-adequate and -deficient rats
| Fatty Acid | Unesterified Fatty Acid
|
Total Fatty Acid
|
||
|---|---|---|---|---|
| Adequate | Deprived | Adequate | Deprived | |
| nmol/ml plasma | ||||
| 14:0 | 57 ± 11 | 64 ± 7.6 | 111 ± 35 | 132 ± 39 |
| 16:0 | 459 ± 108 | 488 ± 60 | 1,677 ± 441 | 1,676 ± 571 |
| 16:1n-7 | 84 ± 25 | 95 ± 15 | 188 ± 78 | 235 ± 99 |
| 18:0 | 96 ± 20 | 95 ± 8.5 | 1,118 ± 125 | 1,069 ± 141 |
| 18:1n-9 | 240 ± 66 | 244 ± 36 | 688 ± 264 | 722 ± 333 |
| 18:1n-7 | 49 ± 12 | 56 ± 18 | 201 ± 62 | 230 ± 96 |
| 18:2n-6 | 259 ± 49 | 253 ± 36 | 1,102 ± 260 | 1,023 ± 368 |
| 18:3n-3 | 27 ± 6.0 | 1.0 ± 0.45c | 51 ± 15 | 3.6 ± 1.2c |
| 20:4n-6 | 25 ± 4.8 | 34 ± 5.9c | 1,361 ± 204 | 1,597 ± 141b |
| 20:5n-3 | 3.3 ± 1.1 | ND | 33 ± 11 | ND |
| 22:5n-6 | ND | 8.7 ± 1.2 | ND | 13 ± 38 |
| 22:5n-3 | 3.6 ± 1.3 | ND | 19 ± 3.1 | ND |
| 22:6n-3 | 6.5 ± 2.6 | 0.23 ± 0.10c | 151 ± 35 | 14 ± 5.9c |
| Total | 1,312 ± 292 | 1,338 ± 171 | 6,719 ± 1,439 | 6,899 ± 1,733 |
| Total n-6 | 285 ± 53 | 295 ± 41 | 2,463 ± 388 | 2,756 ± 529 |
| Total n-3 | 40.7 ± 9.7 | 1.3 ± 0.4c | 246 ± 53 | 17 ± 5.1c |
| Total saturated | 613 ± 134 | 647 ± 73 | 2,906 ± 585 | 2,877 ± 718 |
| Total monounsaturated | 374 ± 101 | 395 ± 61 | 1,077 ± 398 | 1,187 ± 527 |
| 18:3n-3a | 53 ± 5.3 | 33 ± 8.4 | ||
Adapted from (23). Values are means ± SD (n = 10 and 7 for diet-adequate and diet-deficient groups, respectively). ND, not detected.
Unesterified 18:3n-3 concentration in plasma after 5 min of intravenous [1-14C]α-LNA.
P < 0.01, differs significantly from mean in diet-adequate group.
P < 0.001, differs significantly from mean in diet-adequate group.