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Progression-free survival (PFS) of patients with tumor mutation burden above or below the (A) 25th, (B) 50th, (C) 75th, and (D) 90th percentiles. The hazard ratios for PFS at each cut point were as follows: 25th percentile, 1.19 (P = .279); 50th percentile, 1.38 (P = .024); 75th percentile, 1.74 (P = .001); 90th percentile, 2.05 (P = .004).
