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. 2018 Jul 10;7:e38268. doi: 10.7554/eLife.38268

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© 2018, Akbergenova et al

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

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Figure 2. — (A) The left panel displays the distribution of GluRIIA in syt1 nulls (left panel) at the muscle 4 NMJ. The corresponding P_r heatmap is shown on the right. The arrows denote several high P_r sites opposed by bright GluRIIA positive PSDs. (B) AZ release events per second for spontaneous release and evoked by 5 Hz stimulation are shown for syt1 nulls mutants, and for spontaneous release in controls. (C) Frequency distribution of P_r is shown for syt1 nulls and controls. (D) Plot of normalized P_r frequency distribution (from 0 to 1 (max)) for syt1 nulls and controls. (E) Cumulative frequency distribution for normalized release rates for syt1 nulls and controls is shown. One-way ANOVA followed by Dunnett’s multiple comparisons test used for statistical analysis (***=p ≤ 0.001). Error bars represent SEM.