Table 3.
Hazard ratios, 95% CIs, and p values for risk of mortality per standard deviation disadvantage in AH4 score and reaction time summary score
| Unadjusted |
Sex, smoking, SES adjusted |
Fully adjusted |
Selected |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cause of death | Predictor | Hazard ratio | 95% CI | p | Hazard ratio | 95% CI | p | Hazard ratio | 95% CI | p | Hazard ratio | 95% CI | p |
| All Cause | AH4 | 1.29 | 1.20 to 1.38 | <.001 | 1.23 | 1.13 to 1.33 | <.001 | 1.13 | 1.04 to 1.23 | 0.006 | 1.13 | 1.04 to 1.23 | 0.006 |
| RT PC1 | 1.27 | 1.20 to 1.35 | <.001 | 1.24 | 1.16 to 1.32 | <.001 | 1.19 | 1.11 to 1.28 | <.001 | 1.19 | 1.11 to 1.28 | <.001 | |
| CVD | AH4 | 1.30 | 1.15 to 1.48 | <.001 | 1.27 | 1.10 to 1.47 | <.001 | 1.18 | 1.02 to 1.38 | 0.031 | 1.18 | 1.02 to 1.38 | 0.031 |
| RT PC1 | 1.25 | 1.13 to 1.39 | <.001 | 1.23 | 1.11 to 1.38 | <.001 | 1.17 | 1.04 to 1.32 | 0.011 | 1.17 | 1.04 to 1.32 | 0.011 | |
| CHD | AH4 | 1.35 | 1.15 to 1.59 | <.001 | 1.30 | 1.08 to 1.56 | 0.006 | 1.17 | 0.96 to 1.42 | 0.125 | |||
| RT PC1 | 1.32 | 1.16 to 1.49 | <.001 | 1.30 | 1.14 to 1.48 | <.001 | 1.23 | 1.06 to 1.43 | 0.005 | 1.30 | 1.14 to 1.48 | <.001 | |
| Stroke | AH4 | 1.08 | 0.84 to 1.38 | 0.551 | 1.01 | 0.76 to 1.33 | 0.968 | 1.00 | 0.74 to 1.34 | 0.978 | |||
| RT PC1 | 1.06 | 0.82 to 1.36 | 0.678 | 1.03 | 0.78 to 1.34 | 0.847 | 1.03 | 0.77 to 1.37 | 0.849 | ||||
| Cancer: all | AH4 | 1.20 | 1.07 to 1.36 | 0.002 | 1.13 | 0.99 to 1.30 | 0.073 | 1.10 | 0.95 to 1.27 | 0.214 | |||
| RT PC1 | 1.15 | 1.03 to 1.29 | 0.013 | 1.11 | 0.99 to 1.25 | 0.080 | 1.08 | 0.95 to 1.23 | 0.265 | ||||
| Cancer: smoking | AH4 | 1.28 | 1.10 to 1.49 | 0.001 | 1.13 | 0.96 to 1.35 | 0.150 | 1.08 | 0.89 to 1.30 | 0.434 | |||
| RT PC1 | 1.22 | 1.07 to 1.39 | 0.003 | 1.15 | 1.00 to 1.33 | 0.048 | 1.13 | 0.96 to 1.31 | 0.134 | 1.15 | 1.00 to 1.33 | 0.048 | |
| Cancer: other | AH4 | 1.08 | 0.88 to 1.32 | 0.453 | 1.13 | 0.90 to 1.41 | 0.291 | 1.14 | 0.89 to 1.45 | 0.305 | |||
| RT PC1 | 1.02 | 0.83 to 1.26 | 0.842 | 1.03 | 0.83 to 1.28 | 0.776 | 0.98 | 0.78 to 1.25 | 0.898 | ||||
| Respiratory | AH4 | 1.52 | 1.23 to 1.88 | <.001 | 1.38 | 1.08 to 1.77 | 0.010 | 1.20 | 0.92 to 1.57 | 0.173 | |||
| RT PC1 | 1.43 | 1.22 to 1.67 | <.001 | 1.38 | 1.17 to 1.63 | <.001 | 1.30 | 1.08 to 1.57 | 0.005 | 1.38 | 1.17 to 1.63 | <.001 | |
| Digestive | AH4 | 1.33 | 0.97 to 1.83 | 0.079 | 1.33 | 0.92 to 1.91 | 0.127 | 1.16 | 0.78 to 1.71 | 0.465 | |||
| RT PC1 | 1.38 | 1.08 to 1.76 | 0.009 | 1.37 | 1.06 to 1.76 | 0.015 | 1.31 | 0.98 to 1.73 | 0.065 | 1.37 | 1.06 to 1.76 | 0.015 | |
| Dementia | AH4 | 1.24 | 0.89 to 1.72 | 0.198 | 1.06 | 0.73 to 1.53 | 0.750 | 1.02 | 0.69 to 1.51 | 0.908 | |||
| RT PC1 | 1.18 | 0.87 to 1.62 | 0.292 | 1.11 | 0.79 to 1.56 | 0.539 | 1.10 | 0.77 to 1.59 | 0.596 | ||||
Notes: Unadjusted and covariate adjusted results are from separate models for AH4 and RT. The fully adjusted results are for a single model (per cause) that includes the covariates, AH4 and the RT summary score. The Selected model results are derived from the fully adjusted model by backwards elimination whilst retaining the covariates.
AH4 unadjusted and covariate adjusted results are duplicated from Table 2 to facilitate comparison.
AH4 scores are reversed.