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. 2018 Jul-Aug;69:134–145. doi: 10.1016/j.intell.2018.05.005

Table A2.

Results showing effect of adjusting for covariates separately.


Covariates adjusted for

Unadjusted
Sex
Smoking
SES
Cause of death Predictor Hazard ratio 95% CI p Hazard ratio 95% CI p Hazard ratio 95% CI p Hazard ratio 95% CI p
All Cause AH4 1.29 1.20 to 1.38 <.001 1.31 1.22 to 1.40 <.001 1.23 1.14 to 1.33 <.001 1.23 1.14 to 1.34 <.001
CRT mean 1.30 1.22 to 1.38 <.001 1.29 1.21 to 1.38 <.001 1.26 1.17 to 1.35 <.001 1.27 1.18 to 1.35 <.001
SRT mean 1.23 1.15 to 1.31 <.001 1.23 1.15 to 1.31 <.001 1.22 1.15 to 1.31 <.001 1.21 1.13 to 1.29 <.001
CRT SD 1.12 1.05 to 1.20 0.001 1.17 1.10 to 1.25 <.001 1.08 1.01 to 1.16 0.025 1.10 1.03 to 1.18 0.006
SRT SD 1.18 1.11 to 1.26 <.001 1.20 1.12 to 1.28 <.001 1.18 1.10 to 1.26 <.001 1.17 1.09 to 1.25 <.001
CVD AH4 1.30 1.15 to 1.48 <.001 1.34 1.18 to 1.52 <.001 1.25 1.10 to 1.42 <.001 1.25 1.09 to 1.43 0.001
CRT mean 1.29 1.15 to 1.44 <.001 1.28 1.14 to 1.43 <.001 1.24 1.10 to 1.40 <.001 1.25 1.11 to 1.41 <.001
SRT mean 1.21 1.08 to 1.35 <.001 1.21 1.08 to 1.35 <.001 1.20 1.07 to 1.35 0.002 1.18 1.06 to 1.33 0.004
CRT SD 1.13 1.01 to 1.27 0.039 1.23 1.10 to 1.37 <.001 1.09 0.97 to 1.22 0.159 1.11 0.99 to 1.25 0.078
SRT SD 1.16 1.03 to 1.30 0.011 1.19 1.06 to 1.33 0.003 1.15 1.03 to 1.29 0.017 1.14 1.02 to 1.28 0.022
CHD AH4 1.35 1.15 to 1.59 <.001 1.39 1.19 to 1.63 <.001 1.29 1.09 to 1.52 0.003 1.27 1.06 to 1.51 0.008
CRT mean 1.35 1.18 to 1.55 <.001 1.35 1.17 to 1.54 <.001 1.31 1.13 to 1.52 <.001 1.31 1.13 to 1.52 <.001
SRT mean 1.25 1.09 to 1.43 0.002 1.25 1.09 to 1.43 0.001 1.24 1.08 to 1.43 0.003 1.22 1.06 to 1.40 0.007
CRT SD 1.19 1.03 to 1.38 0.020 1.30 1.13 to 1.49 <.001 1.14 0.99 to 1.32 0.075 1.16 1.01 to 1.35 0.043
SRT SD 1.21 1.05 to 1.39 0.008 1.24 1.08 to 1.43 0.002 1.20 1.04 to 1.38 0.012 1.19 1.03 to 1.37 0.016
Stroke AH4 1.08 0.84 to 1.38 0.551 1.10 0.86 to 1.41 0.442 1.03 0.79 to 1.32 0.848 1.01 0.77 to 1.32 0.943
CRT mean 1.10 0.85 to 1.43 0.469 1.09 0.84 to 1.42 0.525 1.05 0.79 to 1.39 0.738 1.06 0.81 to 1.40 0.663
SRT mean 1.08 0.83 to 1.40 0.589 1.08 0.83 to 1.40 0.567 1.07 0.82 to 1.40 0.629 1.05 0.80 to 1.38 0.702
CRT SD 0.95 0.73 to 1.24 0.716 1.02 0.79 to 1.32 0.885 0.92 0.71 to 1.20 0.557 0.94 0.72 to 1.22 0.626
SRT SD 1.02 0.79 to 1.32 0.875 1.04 0.80 to 1.35 0.770 1.02 0.78 to 1.32 0.903 1.01 0.78 to 1.31 0.942
Cancer: all AH4 1.20 1.07 to 1.36 0.002 1.21 1.07 to 1.37 0.002 1.15 1.02 to 1.30 0.026 1.16 1.02 to 1.33 0.028
CRT mean 1.13 0.99 to 1.27 0.061 1.12 0.99 to 1.27 0.065 1.07 0.94 to 1.22 0.290 1.09 0.96 to 1.24 0.191
SRT mean 1.18 1.05 to 1.32 0.005 1.18 1.05 to 1.32 0.005 1.17 1.04 to 1.31 0.009 1.16 1.03 to 1.30 0.014
CRT SD 1.02 0.90 to 1.15 0.751 1.04 0.92 to 1.17 0.547 0.99 0.87 to 1.12 0.838 1.00 0.89 to 1.14 0.943
SRT SD 1.13 1.01 to 1.27 0.034 1.14 1.01 to 1.27 0.028 1.12 1.00 to 1.26 0.047 1.12 1.00 to 1.25 0.055
Cancer: smoking AH4 1.28 1.10 to 1.49 0.001 1.29 1.11 to 1.50 <.001 1.18 1.01 to 1.38 0.037 1.18 1.00 to 1.39 0.048
CRT mean 1.18 1.02 to 1.37 0.025 1.18 1.02 to 1.37 0.029 1.10 0.93 to 1.29 0.261 1.12 0.96 to 1.31 0.150
SRT mean 1.20 1.04 to 1.37 0.010 1.20 1.05 to 1.37 0.009 1.18 1.03 to 1.37 0.020 1.16 1.01 to 1.34 0.036
CRT SD 1.09 0.94 to 1.26 0.270 1.13 0.97 to 1.30 0.109 1.03 0.89 to 1.19 0.692 1.06 0.91 to 1.23 0.444
SRT SD 1.20 1.05 to 1.37 0.008 1.21 1.06 to 1.38 0.005 1.19 1.04 to 1.37 0.013 1.18 1.03 to 1.35 0.018
Cancer: other AH4 1.08 0.88 to 1.32 0.453 1.07 0.88 to 1.31 0.483 1.10 0.90 to 1.35 0.351 1.12 0.90 to 1.40 0.305
CRT mean 1.02 0.81 to 1.27 0.891 1.02 0.82 to 1.27 0.874 1.03 0.83 to 1.29 0.784 1.03 0.82 to 1.29 0.810
SRT mean 1.13 0.93 to 1.38 0.229 1.13 0.92 to 1.38 0.232 1.14 0.93 to 1.39 0.210 1.14 0.93 to 1.39 0.203
CRT SD 0.90 0.72 to 1.12 0.331 0.88 0.70 to 1.10 0.250 0.90 0.72 to 1.13 0.365 0.90 0.72 to 1.12 0.348
SRT SD 0.99 0.80 to 1.23 0.962 0.99 0.80 to 1.23 0.930 1.00 0.81 to 1.24 0.993 1.00 0.80 to 1.24 0.988
Respiratory AH4 1.52 1.23 to 1.88 <.001 1.54 1.24 to 1.91 <.001 1.42 1.14 to 1.78 0.002 1.41 1.12 to 1.79 0.004
CRT mean 1.49 1.27 to 1.75 <.001 1.48 1.26 to 1.74 <.001 1.46 1.21 to 1.75 <.001 1.45 1.22 to 1.72 <.001
SRT mean 1.33 1.12 to 1.58 0.001 1.33 1.12 to 1.57 0.001 1.33 1.11 to 1.58 0.002 1.29 1.08 to 1.55 0.004
CRT SD 1.10 0.90 to 1.35 0.336 1.15 0.94 to 1.41 0.171 1.04 0.85 to 1.28 0.679 1.07 0.87 to 1.31 0.508
SRT SD 1.38 1.18 to 1.63 <.001 1.40 1.19 to 1.65 <.001 1.39 1.18 to 1.65 <.001 1.37 1.16 to 1.61 <.001
Digestive AH4 1.33 0.97 to 1.83 0.079 1.34 0.98 to 1.85 0.070 1.29 0.93 to 1.80 0.129 1.33 0.93 to 1.90 0.113
CRT mean 1.32 0.99 to 1.75 0.055 1.31 0.99 to 1.74 0.058 1.29 0.96 to 1.75 0.095 1.30 0.97 to 1.75 0.075
SRT mean 1.20 0.90 to 1.61 0.212 1.20 0.90 to 1.61 0.209 1.20 0.89 to 1.62 0.231 1.19 0.88 to 1.60 0.252
CRT SD 1.41 1.09 to 1.83 0.010 1.45 1.12 to 1.87 0.005 1.37 1.06 to 1.79 0.018 1.40 1.08 to 1.82 0.012
SRT SD 1.33 1.03 to 1.71 0.031 1.34 1.03 to 1.73 0.026 1.33 1.02 to 1.73 0.033 1.32 1.02 to 1.71 0.036
Dementia AH4 1.24 0.89 to 1.72 0.198 1.24 0.89 to 1.72 0.208 1.21 0.86 to 1.69 0.269 1.09 0.76 to 1.57 0.638
CRT mean 1.28 0.94 to 1.74 0.119 1.28 0.94 to 1.75 0.114 1.25 0.91 to 1.72 0.161 1.21 0.86 to 1.69 0.272
SRT mean 1.17 0.83 to 1.63 0.369 1.17 0.83 to 1.63 0.371 1.16 0.83 to 1.63 0.391 1.12 0.79 to 1.59 0.511
CRT SD 1.07 0.77 to 1.49 0.675 1.06 0.76 to 1.48 0.736 1.06 0.76 to 1.46 0.745 1.03 0.74 to 1.44 0.845
SRT SD 1.02 0.72 to 1.45 0.900 1.02 0.72 to 1.44 0.919 1.02 0.72 to 1.44 0.921 1.00 0.70 to 1.43 0.989
Other Causes AH4 1.30 1.04 to 1.63 0.020 1.32 1.06 to 1.65 0.015 1.27 1.00 to 1.60 0.046 1.28 1.00 to 1.64 0.049
CRT mean 1.62 1.38 to 1.89 <.001 1.60 1.37 to 1.87 <.001 1.63 1.38 to 1.92 <.001 1.61 1.37 to 1.89 <.001
SRT mean 1.39 1.17 to 1.65 <.001 1.39 1.17 to 1.64 <.001 1.39 1.17 to 1.67 <.001 1.38 1.15 to 1.64 <.001
CRT SD 1.32 1.09 to 1.60 0.005 1.37 1.13 to 1.65 0.001 1.28 1.06 to 1.56 0.011 1.30 1.07 to 1.58 0.007
SRT SD 1.18 0.96 to 1.44 0.115 1.19 0.97 to 1.46 0.091 1.18 0.96 to 1.44 0.124 1.17 0.95 to 1.43 0.138

AH4 scores are reversed.