Table A2.
Covariates adjusted for |
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Unadjusted |
Sex |
Smoking |
SES |
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Cause of death | Predictor | Hazard ratio | 95% CI | p | Hazard ratio | 95% CI | p | Hazard ratio | 95% CI | p | Hazard ratio | 95% CI | p |
All Cause | AH4 | 1.29 | 1.20 to 1.38 | <.001 | 1.31 | 1.22 to 1.40 | <.001 | 1.23 | 1.14 to 1.33 | <.001 | 1.23 | 1.14 to 1.34 | <.001 |
CRT mean | 1.30 | 1.22 to 1.38 | <.001 | 1.29 | 1.21 to 1.38 | <.001 | 1.26 | 1.17 to 1.35 | <.001 | 1.27 | 1.18 to 1.35 | <.001 | |
SRT mean | 1.23 | 1.15 to 1.31 | <.001 | 1.23 | 1.15 to 1.31 | <.001 | 1.22 | 1.15 to 1.31 | <.001 | 1.21 | 1.13 to 1.29 | <.001 | |
CRT SD | 1.12 | 1.05 to 1.20 | 0.001 | 1.17 | 1.10 to 1.25 | <.001 | 1.08 | 1.01 to 1.16 | 0.025 | 1.10 | 1.03 to 1.18 | 0.006 | |
SRT SD | 1.18 | 1.11 to 1.26 | <.001 | 1.20 | 1.12 to 1.28 | <.001 | 1.18 | 1.10 to 1.26 | <.001 | 1.17 | 1.09 to 1.25 | <.001 | |
CVD | AH4 | 1.30 | 1.15 to 1.48 | <.001 | 1.34 | 1.18 to 1.52 | <.001 | 1.25 | 1.10 to 1.42 | <.001 | 1.25 | 1.09 to 1.43 | 0.001 |
CRT mean | 1.29 | 1.15 to 1.44 | <.001 | 1.28 | 1.14 to 1.43 | <.001 | 1.24 | 1.10 to 1.40 | <.001 | 1.25 | 1.11 to 1.41 | <.001 | |
SRT mean | 1.21 | 1.08 to 1.35 | <.001 | 1.21 | 1.08 to 1.35 | <.001 | 1.20 | 1.07 to 1.35 | 0.002 | 1.18 | 1.06 to 1.33 | 0.004 | |
CRT SD | 1.13 | 1.01 to 1.27 | 0.039 | 1.23 | 1.10 to 1.37 | <.001 | 1.09 | 0.97 to 1.22 | 0.159 | 1.11 | 0.99 to 1.25 | 0.078 | |
SRT SD | 1.16 | 1.03 to 1.30 | 0.011 | 1.19 | 1.06 to 1.33 | 0.003 | 1.15 | 1.03 to 1.29 | 0.017 | 1.14 | 1.02 to 1.28 | 0.022 | |
CHD | AH4 | 1.35 | 1.15 to 1.59 | <.001 | 1.39 | 1.19 to 1.63 | <.001 | 1.29 | 1.09 to 1.52 | 0.003 | 1.27 | 1.06 to 1.51 | 0.008 |
CRT mean | 1.35 | 1.18 to 1.55 | <.001 | 1.35 | 1.17 to 1.54 | <.001 | 1.31 | 1.13 to 1.52 | <.001 | 1.31 | 1.13 to 1.52 | <.001 | |
SRT mean | 1.25 | 1.09 to 1.43 | 0.002 | 1.25 | 1.09 to 1.43 | 0.001 | 1.24 | 1.08 to 1.43 | 0.003 | 1.22 | 1.06 to 1.40 | 0.007 | |
CRT SD | 1.19 | 1.03 to 1.38 | 0.020 | 1.30 | 1.13 to 1.49 | <.001 | 1.14 | 0.99 to 1.32 | 0.075 | 1.16 | 1.01 to 1.35 | 0.043 | |
SRT SD | 1.21 | 1.05 to 1.39 | 0.008 | 1.24 | 1.08 to 1.43 | 0.002 | 1.20 | 1.04 to 1.38 | 0.012 | 1.19 | 1.03 to 1.37 | 0.016 | |
Stroke | AH4 | 1.08 | 0.84 to 1.38 | 0.551 | 1.10 | 0.86 to 1.41 | 0.442 | 1.03 | 0.79 to 1.32 | 0.848 | 1.01 | 0.77 to 1.32 | 0.943 |
CRT mean | 1.10 | 0.85 to 1.43 | 0.469 | 1.09 | 0.84 to 1.42 | 0.525 | 1.05 | 0.79 to 1.39 | 0.738 | 1.06 | 0.81 to 1.40 | 0.663 | |
SRT mean | 1.08 | 0.83 to 1.40 | 0.589 | 1.08 | 0.83 to 1.40 | 0.567 | 1.07 | 0.82 to 1.40 | 0.629 | 1.05 | 0.80 to 1.38 | 0.702 | |
CRT SD | 0.95 | 0.73 to 1.24 | 0.716 | 1.02 | 0.79 to 1.32 | 0.885 | 0.92 | 0.71 to 1.20 | 0.557 | 0.94 | 0.72 to 1.22 | 0.626 | |
SRT SD | 1.02 | 0.79 to 1.32 | 0.875 | 1.04 | 0.80 to 1.35 | 0.770 | 1.02 | 0.78 to 1.32 | 0.903 | 1.01 | 0.78 to 1.31 | 0.942 | |
Cancer: all | AH4 | 1.20 | 1.07 to 1.36 | 0.002 | 1.21 | 1.07 to 1.37 | 0.002 | 1.15 | 1.02 to 1.30 | 0.026 | 1.16 | 1.02 to 1.33 | 0.028 |
CRT mean | 1.13 | 0.99 to 1.27 | 0.061 | 1.12 | 0.99 to 1.27 | 0.065 | 1.07 | 0.94 to 1.22 | 0.290 | 1.09 | 0.96 to 1.24 | 0.191 | |
SRT mean | 1.18 | 1.05 to 1.32 | 0.005 | 1.18 | 1.05 to 1.32 | 0.005 | 1.17 | 1.04 to 1.31 | 0.009 | 1.16 | 1.03 to 1.30 | 0.014 | |
CRT SD | 1.02 | 0.90 to 1.15 | 0.751 | 1.04 | 0.92 to 1.17 | 0.547 | 0.99 | 0.87 to 1.12 | 0.838 | 1.00 | 0.89 to 1.14 | 0.943 | |
SRT SD | 1.13 | 1.01 to 1.27 | 0.034 | 1.14 | 1.01 to 1.27 | 0.028 | 1.12 | 1.00 to 1.26 | 0.047 | 1.12 | 1.00 to 1.25 | 0.055 | |
Cancer: smoking | AH4 | 1.28 | 1.10 to 1.49 | 0.001 | 1.29 | 1.11 to 1.50 | <.001 | 1.18 | 1.01 to 1.38 | 0.037 | 1.18 | 1.00 to 1.39 | 0.048 |
CRT mean | 1.18 | 1.02 to 1.37 | 0.025 | 1.18 | 1.02 to 1.37 | 0.029 | 1.10 | 0.93 to 1.29 | 0.261 | 1.12 | 0.96 to 1.31 | 0.150 | |
SRT mean | 1.20 | 1.04 to 1.37 | 0.010 | 1.20 | 1.05 to 1.37 | 0.009 | 1.18 | 1.03 to 1.37 | 0.020 | 1.16 | 1.01 to 1.34 | 0.036 | |
CRT SD | 1.09 | 0.94 to 1.26 | 0.270 | 1.13 | 0.97 to 1.30 | 0.109 | 1.03 | 0.89 to 1.19 | 0.692 | 1.06 | 0.91 to 1.23 | 0.444 | |
SRT SD | 1.20 | 1.05 to 1.37 | 0.008 | 1.21 | 1.06 to 1.38 | 0.005 | 1.19 | 1.04 to 1.37 | 0.013 | 1.18 | 1.03 to 1.35 | 0.018 | |
Cancer: other | AH4 | 1.08 | 0.88 to 1.32 | 0.453 | 1.07 | 0.88 to 1.31 | 0.483 | 1.10 | 0.90 to 1.35 | 0.351 | 1.12 | 0.90 to 1.40 | 0.305 |
CRT mean | 1.02 | 0.81 to 1.27 | 0.891 | 1.02 | 0.82 to 1.27 | 0.874 | 1.03 | 0.83 to 1.29 | 0.784 | 1.03 | 0.82 to 1.29 | 0.810 | |
SRT mean | 1.13 | 0.93 to 1.38 | 0.229 | 1.13 | 0.92 to 1.38 | 0.232 | 1.14 | 0.93 to 1.39 | 0.210 | 1.14 | 0.93 to 1.39 | 0.203 | |
CRT SD | 0.90 | 0.72 to 1.12 | 0.331 | 0.88 | 0.70 to 1.10 | 0.250 | 0.90 | 0.72 to 1.13 | 0.365 | 0.90 | 0.72 to 1.12 | 0.348 | |
SRT SD | 0.99 | 0.80 to 1.23 | 0.962 | 0.99 | 0.80 to 1.23 | 0.930 | 1.00 | 0.81 to 1.24 | 0.993 | 1.00 | 0.80 to 1.24 | 0.988 | |
Respiratory | AH4 | 1.52 | 1.23 to 1.88 | <.001 | 1.54 | 1.24 to 1.91 | <.001 | 1.42 | 1.14 to 1.78 | 0.002 | 1.41 | 1.12 to 1.79 | 0.004 |
CRT mean | 1.49 | 1.27 to 1.75 | <.001 | 1.48 | 1.26 to 1.74 | <.001 | 1.46 | 1.21 to 1.75 | <.001 | 1.45 | 1.22 to 1.72 | <.001 | |
SRT mean | 1.33 | 1.12 to 1.58 | 0.001 | 1.33 | 1.12 to 1.57 | 0.001 | 1.33 | 1.11 to 1.58 | 0.002 | 1.29 | 1.08 to 1.55 | 0.004 | |
CRT SD | 1.10 | 0.90 to 1.35 | 0.336 | 1.15 | 0.94 to 1.41 | 0.171 | 1.04 | 0.85 to 1.28 | 0.679 | 1.07 | 0.87 to 1.31 | 0.508 | |
SRT SD | 1.38 | 1.18 to 1.63 | <.001 | 1.40 | 1.19 to 1.65 | <.001 | 1.39 | 1.18 to 1.65 | <.001 | 1.37 | 1.16 to 1.61 | <.001 | |
Digestive | AH4 | 1.33 | 0.97 to 1.83 | 0.079 | 1.34 | 0.98 to 1.85 | 0.070 | 1.29 | 0.93 to 1.80 | 0.129 | 1.33 | 0.93 to 1.90 | 0.113 |
CRT mean | 1.32 | 0.99 to 1.75 | 0.055 | 1.31 | 0.99 to 1.74 | 0.058 | 1.29 | 0.96 to 1.75 | 0.095 | 1.30 | 0.97 to 1.75 | 0.075 | |
SRT mean | 1.20 | 0.90 to 1.61 | 0.212 | 1.20 | 0.90 to 1.61 | 0.209 | 1.20 | 0.89 to 1.62 | 0.231 | 1.19 | 0.88 to 1.60 | 0.252 | |
CRT SD | 1.41 | 1.09 to 1.83 | 0.010 | 1.45 | 1.12 to 1.87 | 0.005 | 1.37 | 1.06 to 1.79 | 0.018 | 1.40 | 1.08 to 1.82 | 0.012 | |
SRT SD | 1.33 | 1.03 to 1.71 | 0.031 | 1.34 | 1.03 to 1.73 | 0.026 | 1.33 | 1.02 to 1.73 | 0.033 | 1.32 | 1.02 to 1.71 | 0.036 | |
Dementia | AH4 | 1.24 | 0.89 to 1.72 | 0.198 | 1.24 | 0.89 to 1.72 | 0.208 | 1.21 | 0.86 to 1.69 | 0.269 | 1.09 | 0.76 to 1.57 | 0.638 |
CRT mean | 1.28 | 0.94 to 1.74 | 0.119 | 1.28 | 0.94 to 1.75 | 0.114 | 1.25 | 0.91 to 1.72 | 0.161 | 1.21 | 0.86 to 1.69 | 0.272 | |
SRT mean | 1.17 | 0.83 to 1.63 | 0.369 | 1.17 | 0.83 to 1.63 | 0.371 | 1.16 | 0.83 to 1.63 | 0.391 | 1.12 | 0.79 to 1.59 | 0.511 | |
CRT SD | 1.07 | 0.77 to 1.49 | 0.675 | 1.06 | 0.76 to 1.48 | 0.736 | 1.06 | 0.76 to 1.46 | 0.745 | 1.03 | 0.74 to 1.44 | 0.845 | |
SRT SD | 1.02 | 0.72 to 1.45 | 0.900 | 1.02 | 0.72 to 1.44 | 0.919 | 1.02 | 0.72 to 1.44 | 0.921 | 1.00 | 0.70 to 1.43 | 0.989 | |
Other Causes | AH4 | 1.30 | 1.04 to 1.63 | 0.020 | 1.32 | 1.06 to 1.65 | 0.015 | 1.27 | 1.00 to 1.60 | 0.046 | 1.28 | 1.00 to 1.64 | 0.049 |
CRT mean | 1.62 | 1.38 to 1.89 | <.001 | 1.60 | 1.37 to 1.87 | <.001 | 1.63 | 1.38 to 1.92 | <.001 | 1.61 | 1.37 to 1.89 | <.001 | |
SRT mean | 1.39 | 1.17 to 1.65 | <.001 | 1.39 | 1.17 to 1.64 | <.001 | 1.39 | 1.17 to 1.67 | <.001 | 1.38 | 1.15 to 1.64 | <.001 | |
CRT SD | 1.32 | 1.09 to 1.60 | 0.005 | 1.37 | 1.13 to 1.65 | 0.001 | 1.28 | 1.06 to 1.56 | 0.011 | 1.30 | 1.07 to 1.58 | 0.007 | |
SRT SD | 1.18 | 0.96 to 1.44 | 0.115 | 1.19 | 0.97 to 1.46 | 0.091 | 1.18 | 0.96 to 1.44 | 0.124 | 1.17 | 0.95 to 1.43 | 0.138 |
AH4 scores are reversed.