Table A3.

Results for cancers broken down into lung cancer and other cancers

		Unadjusted			Sex, smoking, SES adjusted			Fully adjusted			Selected
Cause of Death	Predictor	Hazard ratio	95% CI	p	Hazard ratio	95% CI	p	Hazard ratio	95% CI	p	Hazard ratio	95% CI	p
Lung Cancer	AH4	1.38	1.10 to 1.74	0.005	1.13	0.86 to 1.47	0.376	1.15	0.85 to 1.54	0.362
	CRT mean	1.13	0.90 to 1.42	0.294	0.93	0.71 to 1.22	0.593	0.75	0.52 to 1.09	0.136
	SRT mean	1.19	0.97 to 1.46	0.096	1.14	0.91 to 1.42	0.247	1.05	0.76 to 1.44	0.771
	CRT SD	1.00	0.80 to 1.26	0.996	0.92	0.73 to 1.16	0.484	0.93	0.72 to 1.21	0.600
	SRT SD	1.30	1.08 to 1.57	0.005	1.28	1.05 to 1.56	0.013	1.36	1.06 to 1.74	0.017	1.28	1.05 to 1.56	0.013
Other Cancers	AH4	1.15	1.01 to 1.33	0.042	1.15	0.98 to 1.34	0.089	1.12	0.94 to 1.33	0.215
	CRT mean	1.13	0.98 to 1.31	0.090	1.11	0.95 to 1.29	0.174	0.99	0.79 to 1.24	0.914
	SRT mean	1.18	1.03 to 1.34	0.017	1.17	1.02 to 1.34	0.023	1.22	0.99 to 1.49	0.064	1.17	1.02 to 1.34	0.023
	CRT SD	1.01	0.87 to 1.16	0.905	1.00	0.86 to 1.16	0.983	0.97	0.82 to 1.15	0.738
	SRT SD	1.04	0.91 to 1.20	0.547	1.04	0.90 to 1.20	0.594	0.91	0.75 to 1.10	0.341

Notes: Unadjusted and covariated adjusted results are from separate models for each cognitive variable. The fully adjusted results are for a single model (per cause) that includes the covariates and all cognitive variables. The Selected model results are derived from the fully adjusted model by backwards elimination of non-significant cognitive variables whilst retaining the covariates.

AH4 scores are reversed.