Table 1. Study characteristics of publications included in the systematic review and meta-analysis.
| Study | Cohort study design | Country | Patients | Age | Enrollment period | Lesions n (ESD/EMR) | Main outcome measures 1 |
| Pérez-Cuadrado-Robles (2018) 23 | Single-center, retrospective | Belgium | 150 | 66 (31 – 83) | 2005 – 2017 | 166 (37,129) | En-bloc and complete resection, local recurrence |
| Hoteya (2017) 10 | Single-center, retrospective | Japan | 129 | 61 ± 11.2 (range: 32 – 86) | 2005 – 2015 | 129 (74,55) | En-bloc and complete resection, local recurrence. |
| Teoh (2015) 22 | Multicenter, retrospective | Hong-Kong | 12 | – | 2010 – 2013 | 12 (6,6) | En-bloc resection |
| Nonaka (2015) 12 | Single-center, retrospective | Japan | 113 | 61.7 ± 11.9 | 2000 – 2013 | 121 (8,113) | En-bloc and complete resection, local recurrence |
| Park (2015) 11 | Multicenter, retrospective | Korea | 51 | 59.5 ± 12.5 | 2002 – 2013 | 51 (6,45) | En-bloc and complete resection, local recurrence |
| Inoue (2014) 17 | Single-center, retrospective | Japan | 59 | 58 | 1993 – 2011 | 63 (10,53) | En-bloc resection |
| Basford (2014) 21 | Multicenter, retrospective | United Kingdom | 34 | 69 (48 – 87) | 2005 – 2012 | 34 (13,21) | En-bloc resection, local recurrence |
| Matsumoto (2014) 13 | Single-center, retrospective | Japan | 44 | 65 ± 9 (35 – 79) | 2005 – 2013 | 46 (15,31) | En-bloc and complete resection, local recurrence |
| Yamamoto (2014) 14 | Single-center, retrospective | Japan | 47 | 65.8 ± 12.4 | 2006 – 2013 | 47 (30,17) | En-bloc and complete resection, local recurrence |
| Kakushima (2014) 18 | Single-center, retrospective | Japan | 23 | 68 (43 – 81) | 2002 – 2012 | 23 (13, 10) | En-bloc and complete resection, local recurrence |
| Seo (2014) 15 | Single-center, retrospective | Korea | 40 | 59.9 (39 – 83) | 2003 – 2012 | 40 (7, 33) | En-bloc and complete resection, local recurrence |
| Zhong (2012) 20 | Single-center, retrospective | China | 21 | 55 (29 – 72) | 2007 – 2011 | 21 (9, 12) | En-bloc and complete resection, local recurrence |
| Endo (2010) 19 | Single-center, retrospective | Japan | 16 | 66.5 (53 – 80) | 2005 – 2009 | 16 (5, 11) | En-bloc and complete resection, local recurrence |
| Honda (2009) 16 | Single-center, retrospective | Japan | 14 | 60.7 ± 12 | 2005 – 2008 | 15 (9, 6) | En-bloc resection |
ESD, endoscopic submucosal dissection; EMR, endoscopic mucosal resection
1
All studies but Teoh considered the secondary outcomes (intraoperative/delayed perforation and delayed bleeding).