Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Genetic depletion of p53 in DNA repair deficientErcc1-/Δmice improves healthspan and lifespan. (A) Average age (weeks) of onset for several aging symptoms in Ercc1-/Δ and Ercc1-/Δp53+/- mice. n = 11 Ercc1-/Δp53+/- mice and n = 13 Ercc1-/Δ mice. (B) Kaplan-Meier survival curves of Ercc1-/Δ (n = 119) and Ercc1-/Δp53+/- (n = 11) mice were calculated. Log-rank (Mantel-Cox) test * **p < 0.001.
